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CAS 71-44-3
CAS 306-67-2

shahwada ceeriin

Xawada shahwadu waa spermidine-ka-soo-baxa biogenic biogenic oo laga helay si xad dhaaf ah dhammaan qiimaha pH. Waxaa laga helaa unugyo iyo noole kala duwan, waxay inta badan u dhaqantaa sidii qodob korriin lagama maarmaan u ah noocyada bakteeriyada qaarkood. Shahwada waxay la xiriirtaa asiidhyada nucleic-ka ah, gaar ahaan fayrasyada, waxaana loo maleynayaa inay dejiso qaabka helicalka.

Waxyaabaha ceeriin ee shahwada waxaa ka mid ah saldhigga bilaashka ah ee shahwada CAS 71-44-3 iyo shahwada tetrahydrochloride budada CAS 306-67-2.

Wisepowder waxay awood u leedahay in ay soo saarto oo ay bixiso tiro badan oo ah shahwada lacag la'aanta ah ee alaabta ceeriin iyo shahwada tetrahydrochloride budada.Dhammaan wax soo saarka budada shahwada ee hoos yimaada xaaladda cGMP iyo nidaamka xakamaynta tayada adag, dhammaan dukumiintiyada baaritaanka iyo muunada la heli karo.

Caqligu wuxuu awood u leeyahay inuu soo saaro oo uu bixiyo tiro badan. Dhammaan wax soo saarka ee hoos yimaada xaaladda cGMP iyo nidaamka xakamaynta tayada adag, dhammaan dukumeentiyada imtixaanka iyo muunada la heli karo.
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shahwada Macluumaadka Saldhigga Kiimikada

magaca shahwada, shahwada tetrahydrochloride
CAS 71-44-3, 306-67-2
xagiisayna 98%
Magaca kiimikada N1,N4-Bis (3-aminopropyl) butane-1,4-diamine

N, N'-bis(3-aminopropyl) -1,4-butanediamine
Isku mid ahaanshaha Diaminopropyltetramethylenediamine

N,N'-Bis(3-aminopropyl)butane-1,4-diamine

spermidine 3 HCl

shahwada
Formula kelli C10H26N4
Miisaanka kelli 202.34
Boling Point /
Muhiimadda InChI PFNFFQXMRSDOHW-UHFFFAOYSA-N
Form dareere, budo
Imaanshaha dareere, budo
Nolosha badh /
milmi ku milmay biyaha (50 mg/ml), taasoo keenaysa xal huruud ah oo cad, midna aan lahayn.
kaydinta Xaaladda Ku kaydi heerkulka 2-8 °C. Solutions of saldhig free shahwadu waa

si diyaar ah oksidized. Xalku waa kuwa ugu xasilloon haddii la diyaariyo

biyo deg deg ah oo lagu kaydiyo aliquots barafaysan, hoostooda

argon ama gaaska nitrogen.
Codsiga shahwada antioxidant
Dukumentiga Tijaabinta Available

 

Shayga ceeriin ee shahwada 71-44-3 General Description

Shahwadu waa polyamine endogenous oo leh kooxo badan oo amino ah. Waxaa la ogaaday inay door muhiim ah ka ciyaarto dheef-shiid kiimikaad ee dhammaan unugyada eukaryotic. Waxa kale oo ay isku ururin kartaa DNA-da shahwada sababta oo ah lacagteeda wanaagsan ee xaaladda jireed. Sababtoo ah shahwadu waa molecule endogenous ah oo si ballaaran ugu sugan deegaanka bayooloji, waxaa la filayaa in shahwadu ay lahaan doonto biocompatibility ka wanaagsan ka dibna unugyada kale ee cationic synthetic.

Waxyaabaha ceeriin ee shahwada waxaa ka mid ah saldhigga bilaashka ah ee shahwada CAS 71-44-3 iyo shahwada tetrahydrochloride budada CAS 306-67-2. Saldhigga xorta ah ee shahwadu waa qaab dareere ah, shahwada tetrahydrochloride waa qaab budo cayriin ah.

 

Shayga ceeriin ee shahwada 71-44-3 Taariikhda

Antonie van Leeuwenhoek ayaa markii ugu horreysay ku sharraxay crystals of phosphates shahwada ee shahwada aadanaha 1678. Magaca shahwada waxaa markii ugu horreysay isticmaalay farmashiyihii Jarmalka ee Ladenburg iyo Abel 1888, qaab dhismeedka saxda ah ee shahwada ayaan ugu dambeyntii la aasaasay ilaa 1926, isku mar gudaha England (by Dudley , Rosenheim, iyo Starling) iyo Germany (by Wrede et al.) shahwada waa kiimikaad ugu horrayn mas'uul ka ah sifo urta shahwada.

 

Shayga ceeriin ee shahwada 71-44-3 Farsamaynta Ficilka

Xawada shahwadu waxay ka timaadaa shahwada shahwada synthase. Xawada shahwadu waa polyamine, cations organic yar oo gabi ahaanba looga baahan yahay koritaanka unugyada eukaryotic. shahwada, waxaa caadi ahaan laga helaa xajmiyada millimolar ee nukleus. Xawada shahwadu waxay si toos ah ugu shaqeysaa sidii xagjirnimo xor ah, waxayna samaysaa noocyo kala duwan oo ka hortag ah waxyeelada oksaydhka ee DNA-da. Dhaawaca oksijiinta ee DNA-da ee noocyada ogsijiinta fal-celiska ah waa dhibaato joogto ah oo ay tahay in unugyadu ay iska ilaaliyaan si ay u noolaadaan. Sidaa darteed, shahwadu waa unug dabiici ah oo weyn oo awood u leh inay DNA ka ilaaliyaan weerarka xagjirka ah ee xorta ah. Shahwada waxay sidoo kale ku lug leedahay nidaaminta muujinta hidda-socodka, xasilinta chromatin, iyo ka-hortagga kala-goynta DNA-da dhexdhexaadinta endonuclease.

 

Shayga ceeriin ee shahwada 71-44-3 Codsiga

Shahwadu waa polyamine endogenous oo leh kooxo badan oo amino ah. Waxaa la ogaaday inay door muhiim ah ka ciyaarto dheef-shiid kiimikaad ee dhammaan unugyada eukaryotic. Waxa kale oo ay isku ururin kartaa DNA-da shahwada sababta oo ah lacagteeda wanaagsan ee xaaladda jireed.

Shahwada waxaa caadi ahaan loo isticmaalaa bayoolaji molecular iyo cilmi-baarista bayooloji. Dabeecadda polycationic ee shahwada ee xalka ayaa u oggolaanaysa isticmaalka roobka DNA-da> 100 lammaane oo dherer ah oo ka soo jeeda milix yar oo biyo ah, iyo go'doominta DNA-da ee gelsyada goobta garaaca wadnaha.Spermine ayaa sidoo kale loo adeegsaday go'doominta koromosoomyada iyo isku-darka chromatin. Waxaa loo isticmaali karaa sida a

dhismaha dhismaha ee diyaarinta wakiilada gudbinta hiddasidaha.Kakanaanta shahwada leh DNA si ay u sameeyaan qaybo leh dhexroor <100 nm ayaa la darsay. shahwada waxaa loo isticmaalay in lagu soo saaro DNA.

 

Xawada shahwada Vs spermidine

Xawada la mid ma aha shahwada. Xawada waxaa la sameeyaa iyada oo lagu daro kooxda aminopropyl spermidine by spermine synthase. Xawadu si xoog leh ayay asaasi ahaan ugu leedahay dabeecad ahaan, iyo xalalka aqueous ee pH-ga jireed, dhammaan kooxaha amino-keeda si wanaagsan ayaa loo dallaci doonaa.

Ilaha cuntada wanaagsan ee shahwada laga helo waa farmaajo gaboobay, boqoshaada, soy-ga la soo saaray, digirta, galleyda, iyo badarka oo dhan. Spermidine waxay ku badan tahay cuntada Mediterranean-ka. Marka la barbardhigo: Maaddada shahwada ee ku jirta balasmaha seminalka bani'aadamku way kala duwan yihiin qiyaastii. 15 iyo 50 mg/L (macnaha 31 mg/l).

 

Waa maxay cuntooyinka ay ku badan tahay shahwada?

Spermidine waxaa laga helaa basbaaska cagaarka ah ee cusub, jeermiska qamadiga, cauliflower, brokoli, boqoshaada, iyo farmaajo kala duwan. Xataa xaddi badan ayaa laga helaa soybean ka sida natto, boqoshaada shitake, badarka amaranth iyo durian.

 

Xagee laga helaa shahwada?

Xawada shahwadu waa polyamine, cations organic yar oo gabi ahaanba looga baahan yahay koritaanka unugyada eukaryotic. shahwada, waxaa caadi ahaan laga helaa xajmiyada millimolar ee nukleus. Xawada shahwadu waxay si toos ah ugu shaqeysaa sidii xagjirnimo xor ah, waxayna samaysaa noocyo kala duwan oo ka hortag ah waxyeelada oksaydhka ee DNA-da.

 

Shayga ceeriin ee shahwada 71-44-3 Tixraaca

  1. Dudley, H. W; Rosenheim, O; Starling, W. W (1926). "Dastuurka Kiimikada ee shahwada: Qaab-dhismeedka iyo Isku-dhafka". Wargeyska Biochemical. 20 (5): 1082-1094. doi:10.1042/bj0201082. PMC 1251823. PMID 16743746.
  2. Xie, X., iwm Daraasad is barbar dhig ah oo saddex nooc ah. J. Mol. Biol., 236(4), 1212-1226 (1994).
  3. Wrede, F (2009). "Ueber die aus dem menschlichen Sperma isolierte Base Spermin". Deutsche Medizinische Wochenschrift. 51: 24. doi: 10.1055/s-0028-1136345
  4. Lewenhoeck, D. A (1677). "Indho-indheyn D. Anthonii Lewenhoeck, De Natis E Semine Genitali Animalculis". Dhaqdhaqaaqyada falsafada ee Bulshada Royal ee London. 12 (133–142): 1040–1046. Bibcode:1677RSPT…12.1040A. doi:10.1098/rstl.1677.0068.

 

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