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Isku-darka budada 7P (1890208-58-8) fiidiyow
Isku-darka 7P budada Macluumaadka Saldhigga
magaca | Isugeynta budada 7P |
CAS | 1890208-58-8 |
xagiisayna | 98% |
Magaca kiimikada | 2-[(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide |
Isku mid ahaanshaha | Isdhaafka 7P
CHEMBL3824120 |
Formula kelli | C22H23N3O5S |
Miisaanka kelli | 441.5 g / mol |
Dhibicda Biyaha | Qiyaastii 159 ℃ |
Muhiimadda InChI | NAXWKPFXCOBXLE-UHFFFAOYSA-N |
Form | Solid |
Imaanshaha | White |
Nolosha badh | 1-2h |
milmi | Dhibaato ku jirta ethyl acetate, dichloromethan;
Si tartiib tartiib ah ayey ugu milmaysan tahay methanol; biyaha |
kaydinta Xaaladda | Meel qalalan, oo iftiinka ka bax. |
Codsiga | Compound 7p waxaa loo soo saaray sidii mid ka mid ah taxaneyaal xeryo ah iyada oo ujeedadu tahay in la garto labada-hawlgale ee thromboxane receptor antagonist / synthase inhibitors. |
Dukumentiga Tijaabinta | Available |
Isku-darka 7P budada Tilmaanta Guud
Budada 'Raw Compound 7P' oo kor u qaadeysa duruufaha neurite ee neurons aasaasiga ah ee aasaasiga ah oo laga soo qaatay hippocampus, kilkral cerebral, iyo retina.
Moodh xayawaan ah oo ku saabsan dhaawaca dareemayaasha indhaha, Raw Compound 7P waxaa lagu muujiyey inuu kicinayo koritaanka farqiga-43 axons togan, taasoo muujineysa in firfircoonida firfircoonida ee fitnada neerite ee Raw Compound 7P ay u tarjumeyso dhiirrigelinta dib-u-cusboonaysiinta axon ee vivo.
Isugeynta 7P (1890208-58-8) Taariikh
Compound 7p waxaa loo soo saaray sidii mid ka mid ah taxaneyaal xeryo ah iyada oo ujeedadu tahay in la garto labada-hawlgale ee thromboxane receptor antagonist / synthase inhibitors.
Xaqiiqdii xarunta 7p waxay muujineysaa xulashada prostaglandin I2 synthase (PTGIS, CYP8A1) oo ka sarreysa thromboxane synthase (CYP5A1).
Isku-darka 7P (1890208-58-8) Faa'iidooyinka
- Isbarbar dhig dareenka madaxa qoob ka ciyaarka
- Waxay kor u qaadaa dusha sare ee neurronimada neerfayaasha aasaasiga ah ee asaasiga ah oo laga soo qaatay hippocampus, cortex cerebral, iyo retina.
Isku-darka 7P (1890208-58-8) Daraasad dheeri ah
U habeyn dheeraad ah ee xarunta 7p iyo ballaarinta farsamooyinka ay ku adeegsato dib-u-cusboonaysiinta qalliinka ee vivo waxay bixin doontaa saldhig macquul ah dadaallada mustaqbalka lagu xoojinayo istiraatiijiyadaha daaweynta.
Isugeynta 7P (1890208-58-8) Tixraac
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- Indole carboxylic acid esters oo ah melampomagnolide B waa wakiilada xinjirowga xinjirowga lidka ku ah labada unugyada dhiiga iyo burooyinka adag. Bommagani S, Ponder J, Penthala NR, Janganati V, Jordan CT, Borrelli MJ, Crooks PA. Eur J Med Chem. 2017 Og 18; 136: 393-405. doi: 10.1016 / j.ejmech.2017.05.031. Epub 2017 May 11. PMID: 28525840 Qodobka PMC ee Bilaashka ah
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