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84687-43-4

Astragaloside IV

Astragaloside IV waa saponin bioactive ah oo markii hore laga soocay xididdada dhirta qalalan ee hidde-wadaha Astragalus, oo loo adeegsado dawada dhaqameed ee Shiinaha. LC1 = 3 µM) .3 Waxay joojisaa ku-soo-celinta HAdV-549 waxayna yaraysaa apoptosis-ka ay sababto HAdV-50. Waxay leedahay saameyn difaac oo kaladuwan oo ku saabsan wadnaha, difaaca jirka, dheef shiidka, iyo habdhiska neerfaha.23 Gaar ahaan, waxay yareysaa cabbirka myocardial infakshanka eeyaha marka laqaato kahor xinjirowga wadnaha waxayna yareysaa dib uhabeynta.

Soo-saar: Soosaaris Dufcaddii
Xidhmada: 1KG / bac, 25KG / durbaan
Caqligu wuxuu awood u leeyahay inuu soo saaro oo uu bixiyo tiro badan. Dhammaan wax soo saarka ee hoos yimaada xaaladda cGMP iyo nidaamka xakamaynta tayada adag, dhammaan dukumeentiyada imtixaanka iyo muunada la heli karo.
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Astragaloside IV Macluumaadka Saldhigga budada

magaca Budada Astragaloside IV
CAS 84687-43-4
xagiisayna 50%, 98%
Magaca kiimikada Astragaloside IV
Isku mid ahaanshaha Astrasieversianin XIV;

wareegsan F;

AstraGALOSIDE;

cyclosiversiside F;

Astragalus Polysaccharides;

Soosaarida Astragalus;
Formula kelli C41H68O14
Miisaanka kelli 784.97
Dhibicda Biyaha 295-296 ° C (shiday)
Muhiimadda InChI QMNWISYXSJWHRY-YLNUDOOFSA-N
Form Solid
Imaanshaha Caddaan budo jaalle ah oo cirro leh
Nolosha badh /
milmi Ku milma methanol, ethanol, acetone; Inchloroform aan milmi karin, ethyl acetate iyo dareeraha kale ee dareeraha dabiiciga ah ee daciifka ah.
kaydinta Xaaladda Ku kaydi -20 ° C
Codsiga Vasodilator, antihypertensive, ka hortagga gabowga
Dukumentiga Tijaabinta Available

 

Astragaloside IV budada 84687-43-4 General Description

Astragaloside IV waa pentacyclic triterpenoid oo ah cycloastragenol oo leh beta-D-xylopyranosyl iyo haraaga beta-D-glucopyranosyl ee ku lifaaqan boosaska O-3 iyo O-6 siday u kala horreeyaan. Waxay ka go'antahay Astragalus membranaceus var mongholicus. Waxay leedahay door ahaan EC 4.2.1.1 (carbonic anhydrase) inhibitor, wakiil anti-bararka, wakiil neuroprotective, antioxidant, wakiil pro-angiogenic iyo metabolite dhirta. Waa saponin triterpenoid iyo pritacyclic triterpenoid. Waxay ka timaaddaa cycloastragenol.

 

Astragaloside IV budada 84687-43-4 History

Astragaloside IV waa xarun dhaqameed Shiinaha ah, iyo faa'iidooyinka muhiimka ah waxaa ka mid ah anti-gabowga, kor u qaadista difaaca jirka, hurdo fiican iyo qoto dheer, koritaanka timaha, xoojinta libido, iyo anti-bararka.

 

Astragaloside IV budada 84687-43-4 Mfarsamada Of Action

Astragaloside IV waa nooca cycloartane triterpene glycosides, waa mid ka mid ah maaddooyinka ugu firfircoon firfircoon ee dawada dhaqanka Shiinaha Astragalus membranaceus, oo nuxurkeedu yahay shuruudaha ugu waaweyn ee qiimaynta tayada mudnaanta Astragalus membranaceus. Astragaloside IV waxay leedahay saamayn ka hortagga burooyinka, anti-bararka, antioxidant, hypoglycemic, ilaalinta myocardial, myocarditis-ka ka hortaga fayraska, ilaalinta unugyada maskaxda iyo fayraska ka hortagga cagaarshowga B iwm, waxayna leedahay saamayn ballaadhan oo dawooyin ah.

 

Astragaloside IV Powder 84687-43-4 Cilmi baaris dheeraad ah

Saamaynta dawooyinka ：

  1. Saamaynta Immunomodulatory: Astragaloside IV, Morop peritoneal macrophages iyo Mycobacterium tuberculosis ayaa si wada jir ah loo asaasay si loo tijaabiyo awooda faagocytic ee qaaxada Mycobacterium ee jiifka peritoneal macrophages, iyo waxyaabaha ku jira γ-interferon (IFN-γ) iyo interleukin-1β (IL-1β) dhanka dhaqanka sidoo kale waa la ogaaday.
  2. Saamaynta ilaalinta xubinta, oo ay ka mid yihiin ilaalinta Maskaxda, Kalyaha ilaalinta, Sambabka oo la ilaaliyo, ilaalinta myocardial, ilaalinta beerka
  3. Saameynta Hypoglycemic: Qaadashada jiirka leh nooca-2 ee sonkorowga sida walxaha cilmi baarista si loo barto qawaaniinta astragaloside IV ee enzymes gulukooska cagaarshowga ee jiirka oo leh streptomycin iyo cuntada dufanka badan ee sokorowga keena
  4. Saamaynta anti-apoptotic: astragaloside IV waxay si weyn u yareyn kartaa tilmaanta apoptosis ee unugyada myocardial ee leh CVB3 viral myocarditis.
  5. Anti-barar iyo saamaynta fayraska: astragaloside IV ayaa si weyn u hor istaagtay bararka dhegta ee xylene-ku-keentay jiirarka, oo leh saamayn xooggan oo ka-hortagga bararka.
  6. Saamaynta gabowga.
  7. Dhiirrigelinta faafitaanka unugyada: isku-soo-ururinta habboon ee astragaloside IV waxay dhiirrigelin kartaa kororka degdegga ah ee chondrocytes waxayna dayactiri kartaa waxqabadka chondrocytes, iyadoo la siinayo hab cusub oo loogu talagalay injineernimada unugyada carjawda si loo helo unugyo fara badan iyo in la ilaaliyo howlaha chondrocyte muddo gaaban.

 

Astragaloside IV Powder 84687-43-4 Tixraac

  1. Zhang, Wei-Jian., Et al., 2003. Waxqabadka antiinflammatory ee astragaloside IV waxaa lagu dhexdhexaadiyaa iyadoo la joojinayo firfircoonaanta NF-kappaB iyo muujinta moodeelka mooska. Thrombosis iyo haemostasis. 90 (5): 904-14. PMID: 14597987
  2. Li M, iyo al. Astragaloside IV waxay yareysaa cilladaha garashada ee ay sababaan is-goysyada maskaxda ku-meel-gaadhka ah ee ku-meel-gaadhka ah iyo ku-soo-celinta jiirarka iyada oo loo marayo habab ka hortag ah. Neurosci Lett. 2016 Diisembar 20.
  3. Isaga CS, et al. Astragaloside IV Waxay sare uqaadaa Cisplatin Chemosensitivity ee Unugyada Unugyada Kansarka Sambabka ee Aan Yar Yar iyadoo loo marayo Kahortaga B7-H3. Qalabka Physiol Biochem. 2016; 40 (5): 1221-1229. Epub 2016 Diseembar 14.

 

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