3,4-Dihydroxybenzoic acid budada 99-50-3

3,4-Dihydroxybenzoic acid budada Macluumaadka Saldhigga Kiimikada

3,4-Dihydroxybenzoic acid budada 99-50-3 General Description

Powder 3,4-dihydroxybenzoic acid sidoo kale si fiican loo yaqaan Protocatechuic acid (PCA), waa dihydroxybenzoic acid kaas oo kooxaha hydroxy ay ku yaalaan jagooyinka 3 iyo 4. Waxay leedahay door sida metabolite xenobiotic aadanaha, metabolite dhirta, wakiilka antineoplastic, EC 1.1.1.25. 1.14.11.2 (shikimate dehydrogenase) inhibitor iyo EC XNUMX (procollagen-proline dioxygenase) inhibitor ah. Waa xubin ka mid ah catechols iyo dihydroxybenzoic acid. Waxay ka timaadaa benzoic acid. Waa a acid conjugate 3,4-dihydroxybenzoate.

3,4-Dihydroxybenzoic acid budada 99-50-3 Mfarsamada Of Action

3,4-Dihydroxybenzoic acid ayaa lagu soo warramey in ay keento apoptosis unugyada leukemia-ga bini'aadamka, iyo sidoo kale unugyada HSG1 ee xun ee laga soo qaatay godadka afka ee bini'aadamka, laakiin 3,4-Dihydroxybenzoic acid ayaa la ogaaday in ay saameyn isku dhafan ku leedahay TPA-ku-jirta burooyinka maqaarka ee jiirka. Iyada oo ku xidhan tirada PCA-ga iyo wakhtiga ka horreeya codsiga, PCA-ga waxa uu yarayn karaa ama kor u qaadi karaa koritaanka burada. Sidoo kale, 3,4-Dihydroxybenzoic acid ayaa lagu soo warramey inay kordhiso faafinta oo ay joojiso apoptosis ee unugyada stem neural. In vitro model oo isticmaalaya unugyada leukemia HL-60, protocatechuic acid waxay muujisay saameyn antigenotoxic ah iyo dhaqdhaqaaqa tumoricidal.In laba baaritaan oo preclinical, protocatechuic acid ka Hibiscus sabdariffa waxay muujisay awood aad u fiican oo lagu xakameynayo soo celinta fayraska herpes simplex nooca 2 iyo si xoog leh. demciso dhaqdhaqaaqa catalytic ee urease.

Waa maxay 3,4-Dihydroxybenzoic acid budada loo isticmaalo?

3,4-Dihydroxybenzoic acid budada waxaa loo isticmaalaa in lagu sameeyo cuntada kaabista caafimaadka jidhka. 17 faa'iidooyinka 3,4-Dihydroxybenzoic acid waa:

1. Antioxidant adag

3,4-Dihydroxybenzoic acid waxaa loo tixgeliyaa inay tahay qayb firfircoon oo ka mid ah daawooyinka dhirta dhaqameed ee Shiinaha sida Cibotium barometz (L.) JS, Stenoloma chusanum (L.) Ching, Ilex chinensis Sims. Miraha Ficus waa il qani ah oo laga helo xeryahooda polyphenolic iyo flavanoids kuwaas oo mas'uul ka ah sifooyinka antioxidant xoog leh kuwaas oo ka caawiya ka hortagga iyo daaweynta cudurrada kala duwan ee cadaadiska oksida ee la xiriira sida neurodegenerative iyo cudurada beerka. Saliida Acai, oo laga helo midhaha timirta Acaí (Euterpe oleracea) [20], waxay qani ku tahay protocatechuic acid (630 36 mg/kg). Saliida Acai waxay leedahay maaddo xad dhaaf ah oo polyphenols ah, taas oo iyaduna lala xiriiriyay noocyo kala duwan oo la soo sheegay (inta badan vitro) antioxidant, anti-bararka, antiproliferative, iyo guryaha ilaalinta wadnaha. PCA sidoo kale waxay ku dhacdaa tiro qani ah miraha kala duwan sida berry (raspberry, blueberry, bulberry, strawberry, cranberry, iyo gooseberry). Waxa kale oo la og yahay inay ku dhacdo miro Loquat, khamri, malab, iyo soybean.

2. Iska caabbinta basasha

3,4-Dihydroxybenzoic acid waxay ku dhacdaa miisaanka basasha midabaysan Allium cepa taas oo u sahlaysa inay iska caabiyaan smudge basasha, cudur fangas ah oo ay sabab u tahay Colletotrichum circinans.

3. Sifooyin ka hortag ah oo wanaagsan

3,4-Dihydroxybenzoic acid waxa kale oo laga helaa Karootada (Daucus carota) iyo boqoshaada sida Agaricus bisporus (White Button Mushroom) ama Phellinus linteus waxana uu muujiyay sifooyin kiimiko oo wanaagsan.

4. Dhaqdhaqaaqa ka hortagga bakteeriyada

Roselle calyx (Hibiscus sabdariffa L.) laga soosaaray iyo aashitada protocatechuic ayaa labaduba la ogaaday inay hoos u dhigaan heerarka oksaydhka dufanka ee unugyada hilibka lo'da. Protocatechuic acid sidoo kale waxay muujisay saameyn ku-tiirsanaanta qiyaasta.

5. Dhaqdhaqaaqa ka hortagga sonkorowga

Protocatechuic acid at 1% iyo 2% marka la siiyo d-galactose jiirarka daaweeyay ee toddobaadyada 8 ayaa hoos u dhacay heerarka noocyada oksijiinta falcelinta, borotiinka carbonyl, carboxymethyllysine, pentosidine, sorbitol, fructose, iyo methylglyoxal.

6. Dhaqdhaqaaqa Ka hortagga Kansarka

PCA waxay u muuqataa inay leedahay awood ka hortag ah sababtoo ah waxay joojisaa kansarka kiimiko ee vitro waxayna ku kordhisaa saamaynta proapoptotic iyo antiproliferative unugyo kala duwan

7. Dhaqdhaqaaqa ka hortagga boogaha

Habka wax-qabadka PCA-ga ethyl ester waxaa laga yaabaa inay sabab u tahay ficilka cytoprotective ee daroogada ama iyadoo la xoojinayo xuubka gastric si kor loogu qaado difaaca xuubka. Sidoo kale protocatechuic acid waxa kale oo laga yaabaa inay lahaato heer gaar ah oo guryaha lidka ku ah.

8. Dhaqdhaqaaqa ka hortagga gabowga

Protocatechuic acid oo ka soo jeeda miraha engegan ee Alpinia oxyphylla ayaa caddaysay inay tahay xarun ka hortag ah oo suurtagal ah oo ku saabsan beeryarada iyo nidaamka antioxidant-ka ee jiirka da'da ah.

9. Waxqabadka Antifibrotic

Cilmi-baaristu waxay muujisay aldehyde protocatechuic inay leedahay saameyn faa'iido leh oo antifibrogenic ah. Beddelka isbeddelka koritaanka-β1 (TGF-β1) iyo korriinka isbeddelka isbeddelka isku-xirnaanta (CTGF) waxay la xiriiraan pathophysiology ee fibrosis beerka.

10. Faa'iidooyinka kale

Hibiscus protocatechuic acid (PCA) waa iskudhis phenolic fudud oo ka go'doonsan ubaxyada la qalajiyey ee Hibiscus sabdariffa L., oo ah dawo dhireed Shiineys ah, oo la soo sheegay inay tahay:

antiseptic

aphrodisiac

astringent

cholagogue

ba'an

dheefshiidka

diuretic

dareen leh

purgative

Chill

go'aansan

daweynta

caloosha

iyo tonic

Sidoo kale kani waa daawo dadwayne oo loogu talagalay nabarrada, xaaladaha biliijka, kansarka, qufaca, daciifnimada, dyspepsia, dysuria, qandho, hunguriga, xanuunada wadnaha, hypertension, neurosis, scurvy, iyo stranguriy.

11. Waxqabadka Antiviral
12. Ka-hortagga bararka, xanuunka xanuunka, iyo sifooyinka jeermiska
13. Hawlaha Antiatherosclerotic iyo Hyperlipidemic
14. Dhaqdhaqaaqa Wadnaha
15. Hawlaha Hepatoprotective
16. Saameynta Nafsiga
17. Saamaynta habka taranka

3,4-Dihydroxybenzoic acid budada 99-50-3 Codsiga

Kaabista cuntada, antioxidant

3,4-Dihydroxybenzoic acid budada 99-50-3 Baadhis dheeraad ah

Protocatechuic acid, oo sidoo kale loo yaqaan protocatechuate ama 3,4-dihydroxybenzoate, waxay ka tirsan tahay fasalka xeryahooda organic ee loo yaqaan 'hydroxybenzoic acid derivatives'. Derivatives Hydroxybenzoic acid waa xayndaabyo ka kooban hydroxybenzoic acid (ama derivative), kaas oo ah giraanta benzene oo sita carboxyl iyo kooxaha hydroxyl. Enzyme protocatechuate 3,4-dioxygenase waxay isticmaashaa 3,4-dihydroxybenzoate iyo O2 si ay u soo saarto 3-carboxy-cis,cis-muconate. Protocatechuic acid waa daawo. Marka la eego qallafsanaanta isku midka ah ee baranbaro ootheca, walaxda phenolic ee khuseeya waa protocatechuic acid. Protocatechuic acid waa mid khafiif ah, balsamic ah, iyo iskudhis dhadhaminta phenolic. Ka baxsan jidhka bini'aadamka, protocatechuic acid waxaa laga helaa, celcelis ahaan, diiradda ugu sareysa ee dhowr cunto oo kala duwan, sida basasha beerta, budada kookaha, iyo anise star iyo in diirada hoose ee lentils, khamriga, iyo raspberries cas. Protocatechuic acid ayaa sidoo kale la ogaaday, laakiin aan lagu qiyaasin dhowr cunto oo kala duwan, sida fungus dhegta Cloud, pokeweeds Maraykanka, boqoshaada caadiga ah, miraha, iyo feijoa. Tani waxay ka dhigi kartaa aashitada protocatechuic mid biomarker suurtagal ah oo loogu talagalay isticmaalka cuntooyinkan. Waxa kale oo laga helaa Allium cepa (17,540 ppm). Waa dheef-shiid kiimikaad weyn oo ah polyphenols-ka-antioxidant ee laga helo shaaha cagaaran. Sidoo kale, PCA-ga ayaa la sheegay inay kordhiso fidinta oo ay joojiso apoptosis ee unugyada stem neural. Tijaabada vitro-ga ayaa diiwaangelisay antioksidanter iyo anti-bararka firfircoonida PCA, halka ilaalinta beerka ee vivo lagu cabiray calamadaha kiimikada iyo qiimaynta taariikhiga ah.

3,4-Dihydroxybenzoic acid Ilaha

1. 3,4-Dihydroxybenzoic acid waxa laga go'doomi karaa jilif jireed ee Boswellia dalzielii. iyo caleemaha Diospyros melanoxylon.
2. Saliida Açaí, oo laga helo midhaha timirta açaí (Euterpe oleracea), waxay qani ku tahay protocatechuic acid (630± 36 mg/kg). 3,4-Dihydroxybenzoic acid sidoo kale waxay ku jirtaa maqaarka qaar ka mid ah noocyada basasha sida habka antifungal, kordhinta iska caabbinta endogenous ka hortagga fungus smudge. Waxa kale oo laga helaa Allium cepa (17,540 ppm).
3. 3,4-Dihydroxybenzoic acid waxay ku dhacdaa roselle (Hibiscus sabdariffa), kaas oo aduunka oo dhan loo isticmaalo cunto iyo cabitaan ahaan.
4. 3,4-Dihydroxybenzoic acidis ayaa sidoo kale laga helaa boqoshaada sida Agaricus bisporus ama Phellinus linteus.
5. 3,4-Dihydroxybenzoic acidis waxaa loo arkaa qayb firfircoon oo ku jirta daawaynta dhirta dhaqameed ee Shiinaha sida Stenoloma chusanum (L.) Ching, Ilex chinensis Sims, Cibotium barometz (L.) J.Sm.

iibso 3,4-Dihydroxybenzoic acid Powder

3,4-Dihydroxybenzoic Budada acid sida qayb ka mid ah isticmaalka si ay u sameeyaan supplements cuntada, waa iibinta caanka ah online ee suuqa gabowga anti. Budada xigmadda leh waxay soo saartaa oo keentaa tiro badan 3,4-Dihydroxybenzoic acid budo, daahirnimo oo aan ka yarayn 98%, muunad iyo dukumeenti tijaabo ah oo la heli karo.

3,4-Dihydroxybenzoic acid budada 99-50-3 Tixraaca

1. Anter, J.; Romero Jiménez, M.; Fernández Bedmar, Z.; Villatoro Pulido, M.; Analla, M.; Alonso Moraga, A.; Muñoz Serrano, A. (Maarso 2011). "Antigenotoxicity, cytotoxicity, iyo apoptosis induction by apigenin, bisabolol, iyo protocatechuic acid." Joornaalka Cunnada Daawada. 14 (3): 276–
2. Xasan, STS; Švajdlenka, E. (Oktoobar 2017). "Qiimaynta bayoolojiga iyo xidhitaanka molecular ee protocatechuic acid ka Hibiscus sabdariffa L. sida urease ka hortag ah oo awood leh hab ku salaysan ESI-MS". Molecules 22 (10): 1696.
3. Lee, Y.-S.; Kang, YH; Jung, JY; iyo al. (Oktoobar 2008). "Cudurka glycation-ka borotiinka ee ka yimaada jidhka miraha ee Phellinus linteus". Bayoolaji & Daawooyinka Bulletin. 31 (10): 1968-72. doi:10.1248/bpb.31.1968. PMID 18827365.
4. Babich, H.; Sedletcaia, A.; Kenigsberg, B. (Noofambar 2002). "In vitro cytotoxicity of protocatechuic acid ee unugyada bini'aadamka ee ka soo baxa unugyada afka: ku lug lahaanshaha cadaadiska oksaydhka". Farmashiistaha & Cilmiga Sunta. 91 (5): 245-253. doi:10.1034/j.1600-0773.2002.910505.x. PMID 12570031