Products
Taxifolin (dihydroquercetin) budada 480-18-2
Taxifolin (dihydroquercetin) budada Macluumaadka Saldhigga Kiimikada
| magaca | Taxifolin (dihydroquercetin) |
| CAS | 480-18-2 |
| xagiisayna | 98% |
| Magaca kiimikada | 5,7,3′,4′-flavan-on-ol |
| Isku mid ahaanshaha | Dihydroquercetin
Taxifoliol Distylin (+)-Taxifolin trans-Dihydroquercetin (+)-Dihydroquercetin |
| Formula kelli | C15H12O7 |
| Miisaanka kelli | 304.25 |
| Barta Boling | / |
| Muhiimadda InChI | CXQWRCVTCMQVQX-LSDHHAIUSA-N |
| Form | budo |
| Imaanshaha | jaalaha ah |
| Nolosha badh | / |
| milmi | (±) -Taxifolin waxay leedahay milmayn qiyaastii 0.5 mg / ml 1: 1 xal DMSO: PBS (pH 7.2) iyadoo la isticmaalayo habkan. |
| kaydinta Xaaladda | RT |
| Codsiga | kaabayaasha cuntada |
| Dukumentiga Tijaabinta | Available |
Taxifolin (dihydroquercetin) budada 480-18-2 Taariikhda
Ceyriin Taxifolin waa flavonoid awood leh.
Bartamihii 1950-meeyadii, saynisyahannadu markii ugu horreysay waxay go'doomiyeen xaruntan waxayna ku tilmaameen taxifoline ama dihydroquercetin, taas oo kiimiko ahaan la mid ah quercetin ama rutin, laakiin leh astaamo kala duwan.
Taxifolin (dihydroquercetin) budada 480-18-2 Mfarsamada Of Action
Taxifolin ma aha mutagenic oo ka sun yar marka loo eego quercetin ka kooban ee la xidhiidha. Waxay u shaqeysaa sidii wakiilka suurtagalka ah ee ka-hortagga kiimiko iyadoo lagu xakameynayo hiddo-wadaha iyada oo loo marayo habka ku-tiirsanaanta ARE.Taxifolin waxay muujisay inay joojiso koritaanka unugyada kansarka ugxan-sidaha qaab ku-tiirsanaan ah. Si kastaba ha ahaatee, isla daraasaddan, taxifolin waxay ahayd flavonoid ugu waxtarka yar ee joojinta ee muujinta VEGF. Waxa kale oo jira xidhiidh xooggan (oo leh isku xidhka isku xidhka 0.93) ee u dhexeeya saamaynta antiproliferative ee taxifolin derivatives ee maqaarka maqaarka ee fibroblasts iyo unugyada kansarka naasaha aadanaha.
Taxifolin waxay muujisay inay saameyn liddi ku ah faafin ku leedahay noocyo badan oo unugyada kansarka ah iyadoo la joojinayo lipogenesis unugga kansarka. Iyadoo la xakameynayo synthase fatty acids ee unugyada kansarka, taxifolin waxay awood u leedahay inay ka hortagto koritaanka iyo fiditaanka unugyada kansarka.
Awoodda taxifolin si ay u kiciso sameynta fibril iyo kor u qaadida xasilinta noocyada fibrillar ee kolajka ayaa loo isticmaali karaa daawada. Sidoo kale taxifolin waxay joojisay melanogenesis-ka gacanta si wax ku ool ah sida arbutin, mid ka mid ah wakiilada hypopigmenting ee aadka loo isticmaalo ee qurxinta. Si kastaba ha noqotee, arbutin wuxuu u shaqeeyaa sida quercetin oo aad u mutagenic, kansar iyo sun ah.
Taxifolin (dihydroquercetin) budada 480-18-2 Codsiga
Budada Taxifolin (dihydroquercetin) ayaa lagu muujiyay inay saameyn aad u wanaagsan ku leedahay isbeddelada qaar ee unugyada jirka, gaar ahaan kuwa aan la rabin. Ku dhawaad 600 oo daraasadood ayaa la daabacay - intooda badan waxay ku sugan yihiin Ruushka, waxayna ka hadlaan saamaynta togan ee taxifolin, flavonoid awood leh oo ka soo jeeda larch Siberian. Haddaba, waa maxay faa'iidooyinka Taxifolin (dihydroquercetin) ee kaabista cuntada iyo caafimaadka?
Taxifolin (Dihydroquercetin) waa flavonoid awood leh oo sidoo kale laga heli karo oo laga iibsan karo suuqa qaab budo cayriin ah.
Dadaal badan ayaa lagu bixiyaa xaqiijinta iyo muujinta ficilka dihydroquercetin - meelaha ugu muhiimsan ee cilmi-baarista noocan oo kale ah ayaa ah kuwan soo socda:
Saamaynta taxifolin ee dhexdhexaadiyeyaasha bararka iyo cudurrada sida kansarka.
Saamaynta taxifoline iyo saamaynta saarista myeloperoxidase
Saamaynta taxifolin ee waxyeelada fibroblast maqaarka
Saamaynta taxifoline ee nidaamka collagenase I ee unugyada maqaarka ee UVB-daaweeyay
Saamaynta taxifolin ee unugyada iyo saamaynta cytoprotective ee suurtogalka ah
Xogta guud ee laga helay tiro daraasado ah ayaa soo jeedinaya in: quercetin, taxifolin (Dihydroquercetin), iyo quercitrin ay ka faa'iidaysan karaan gaabinta gabowga maqaarka ee bini'aadamka.
Faa'iidooyinka kale ee Taxifolin ee kaabisyada caafimaadka iyo cuntada waxaa ka mid noqon kara:
- Taxifolin (Dihydroquercetin)waa flavonoids awood leh
Waxay ahayd bartamihii 1950-meeyadii markii ugu horreysay ee saynisyahannadu ay soo saareen oo ay ku tilmaameen taxifolin, ama dihydroquercetin, taas oo ah analoogga quercetin ama rutin laakiin leh sifooyin kala duwan. Waxay soo bandhigtaa waxqabadyada fiitamiin P, waxay kor u qaaddaa xuubka xididdada dhiigga waxayna yaraynaysaa xasaasiyadda iyo falcelinta bararka, waxayna sidoo kale leedahay sifooyin badan oo aan la wadaagin inta badan bioflavonoids kale. Sidaa darteed Taxifolin waxay fulisaa saameyn aad uga awood badan antioxidant marka loo eego inta badan flavonoids.
- Taxifolin (Dihydroquercetin)waxay joojisaa cadaadiska oksaydhka iyo bararka
Taxifolin ama Dihydroquercetin ayaa lagu muujiyay inay yihiin dhexdhexaadiye awood leh oo ka mid ah xagjiriinta xorta ah, oo awood u leh inay burburiyaan laba ka mid ah noocyada ugu khatarta badan ee jidhka bini'aadamka: radicals superoxide iyo peroxide. Waxay kaloo ka shaqeysaa ilaalinta unugyada dhiigga cas iyo caddaanka. Daraasaduhu waxay muujinayaan inuu unugyada dhiigga cad ka ilaaliyo waxyeellada deegaanka, iyo in unugyada dhiigga cas ay ka hortagaan dhimashada unugyada oksidafigga ah.
- Taxifolin (Dihydroquercetin)faa'iido u leh daaweynta kansarka
Daraasado badan ayaa muujiyay in taxifolin ay awood u leedahay inay xaddido koritaanka khadadka unugyada kansarka. Unugyada kansarka naasaha iyo unugyada kansarka ugxansidaha waa laba nooc oo malignancies ah oo taxifolin ay muujisay suurtagalnimada in la dilo.
- Taxifolin (Dihydroquercetin)Saamaynta kabka cuntada waxay la xiriirtaa COVID oof-wareen
Cilmi-baarayaal Ruush ah ayaa baaraya saameynta kabka cuntada ee Taxifolin ay ku leedahay dadka ka soo kabanaya oof wareenka la xiriira COVID. Waxaa la bilaabay 2021, tijaabadan caafimaad waxay ku lug leedahay isticmaalka 30 milligram (mg) ee Taxifolin Aqua maalin kasta 100 bukaan. Cilmi-baadhayaashu waxay rajeynayaan inay caddeeyaan sida kaabista cuntada ay u saameyn karto shaqada neefsashada, xaaladda derbiga halbowlaha, iyo tayada guud ee nolosha.
- Taxifolin (Dihydroquercetin)faa'iidooyinka ku saabsan hypertension
Taxifolin waxay leedahay sifooyin kala duwan oo laga yaabo inay faa'iido u leeyihiin kuwa qaba hypertension. Daraasadaha caafimaadku waxay muujiyeen in ay wanaajiso dabacsanaanta erythrocytes si ay u awoodaan inay si fudud u galaan xitaa xididdada dhiigga ee jilicsan. Kor u kaca cadaadiska mar dambe ma dhicin dabcan sidaas darteed khatarta istaroogga ayaa si aad ah hoos ugu dhacaysa. Taxifolin waxay sidoo kale hoos u dhigtaa viscosity-ka dhiigga waxayna wanaajisaa microcirculation ee heerka xididka.
Daraasado kala duwan ayaa lagu sameeyay xaaladdan Ruushka. Saamaynta Taxifolin ayaa lagu baadhay laba kooxood oo 40 bukaan ah oo qaba asthenia neuro-circulatory (nooc ka mid ah tachycardia) oo leh hypertonia iyo hypertension arterial. Iyadoo labada kooxoodba la siiyay hypotensive, kooxda labaad waxay sidoo kale heleen qiyaasta maalinlaha ah ee 40mg ee taxifolin. Kooxda koowaad, saameyn cad oo hypotensive ayaa lagu arkay inta u dhaxaysa maalmaha saddexaad iyo afaraad ee daaweynta laakiin 17% kaqeybgalayaashu waxay u baahdeen kordhinta qiyaasta daawada. Saamaynta hypotensive isku mid ah ayaa lagu arkay kooxda labaad laakiin si dhakhso ah - inta u dhaxaysa maalmaha koowaad iyo labaad ee daaweynta - midkoodna kooxdan uma baahna in daawadooda la kordhiyo.
- Taxifolin (Dihydroquercetin)faa'iido u leh daawaynta cudurka cerebrovascular
Kaabista taxifolin ayaa lagu muujiyay inay hagaajinayso dhibaatooyinka qaarkood, gaar ahaan madax-xanuun, hurdo la'aan, dhibaatooyinka asthenic iyo vascular-daaqsinka iyo sidoo kale vertigo. Hagaajinta ayaa aad muhiim ugu ah bukaanada qaba xanuunka encephalopathy ee ku xiran dhibaatooyinka xididdada dambe ee istaroogga. Waxa kale oo ay hoos u dhigtay niyadda dareenka, xanaaqa, welwelka, niyad jabka, hypochondria iyo hagaajinta dareenka shakhsi ahaaneed. Mar labaad, marka laga reebo niyadda hoose iyo hypochondria, horumarintan ayaa ku weynaaday bukaannada istaroogga. Tilmaamaha dhaqdhaqaaqa xusuusta garaadka ayaa ka fiicnaa saddex-meelood laba meelood bukaannada ka dib maamulka taxifolin, sida feejignaanta iyo feejignaanta. Xusuusta bukaanka ayaa kor u kacday 70% iyo mugga xusuusta hawlgalka ayaa kordhay 66.7% kiisaska.
Xogta laga helay daraasado ku saabsan bukaanada da'da dhexe ee qaba encephalopathy discurculatory waxay muujineysaa in taxifolin ay sameyso saameyn dhexdhexaad ah oo la xiriirta hababka dhexe ee habaynta daaqsinka iyo dareenka nafsiyeed.
Labo daraasadood oo caafimaad ayaa lagu sameeyay 52 bukaan si loo qiimeeyo saameynta 21 maalmood ee maamulka taxifolin oo ay weheliso fitamiin C ee bukaannada qaba dhibaatooyinka wareegga maskaxda. Kaabista ayaa keentay hoos u dhaca viscosity dhiigga iyo xinjirowga-samaynta u janjeera, hagaajinta xusuusta, dareenka iyo waxqabadka maskaxda, hoos u dhaca vertigo, hababka hurdo caadi ah, nafiska madax xanuun iyo daal yar. Wax isbedel ah laguma arag koox placebo.
Taxifolin (Dihydroquercetin) kale hcaafimaadka bfaa'iidooyinka iyo uSES
-Taxifolin iyo cudurrada wadnaha iyo xididdada dhiigga, taxifolin waxay joojisay peroxidation ee serum iyo lipids beerka ka dib shucaaca ionizing sun ah.
-Waxay ka hortagtaa dhibaatooyinka xanuunka macaanka,taxifolin-ku waxa ay joojisaa firfircoonida caabuqa ee neutrophils ee nooca 2-aad ee macaanka waxana laga yaabaa in ay ka ilaaliso habka xididada xididada waxyeelada xanuunka.
-Waxay ilaalisaa habdhiska dhexe ee neerfayaasha oo caafimaad qaba,Taxifolin waxa ay siisaa ilaalin lama huraan u ah maskaxda iyo neerfayaasha.
-Ilaalinta dhaawaca beerka iyo cagaarshow, sababtoo ah Taxifolin awoodda antioxidant ee muhiimka ah, taxifolin waxay ka ilaalin kartaa beerka inay soo gaarto suntan iyo sidoo kale fayrasyada labadaba.
-Waxay kor u qaadaa hab-dhiska difaaca, cilmi-baadhisyadu waxay soo jeedinayaan in taxifolin laga yaabo inay ka caawiso la dagaallanka caabuqyada halista ah sida oof-wareen ama HIV.
Taxifolin (dihydroquercetin) budada 480-18-2 Cilmi baaris dheeraad ah
Taxifolin (dihydroquercetin) Vs Quercetin: keebaa awood leh? Taxifolin ma la mid tahay quercetin?
1. Farqiga ugu horreeya ee u dhexeeya quercetin iyo dihydroquercetin waa inay u muuqdaan inay ka yimaadaan ilo kala duwan oo dhir ah.Taxifoline (dihydroquercetin) iyo Quercetin waa labadaba flavonoids. Flavonoids waa midabada dhirta laga helo cuntooyin iyo dhir badan sida dhirta liinta, shaaha, khamriga cas, berry midab leh, iyo xitaa shukulaatada madow. Waxay xitaa ka dhigi karaan fitamiin C xitaa ka sii xoog badan oo sii waaraya jirka.
Flavonoids waxay ka kooban yihiin qiyaastii 60% 8,000 polyphenols la yaqaan, xeryahooda dhirta u shaqeeya sida antioxidants ee jirkaaga, la dagaallanka xagjirnimada xorta ah. La'aanteed ilaalinta antioxidants ku filan si ay u baabi'iso xagjirka xorta ah ee xad-dhaafka ah, waxay dhaawici karaan unugyadaada.
Quercetin waxa laga helaa qadhaadhka, dhuxusha gudeed ee liinta, miraha kale sida jeeriga iyo tufaaxa, khudaarta sida kaluunka iyo brokoli, miraha, badarka, iyo basasha cas. Dihydroquercetin, oo sidoo kale loo yaqaan taxifolin, ayaa caadi ahaan laga helaa basasha, yamaaruggii caanaha, canabka, shaaha cagaaran, saliidda saytuunka, iyo jilif geedka geedaha qaar ka mid ah.
2. Farqiga labaad ee ugu weyn ee u dhexeeya Taxifolin (dihydroquercetin) iyo quercetin waa inay leeyihiin qurxiyo kiimiko oo kala duwan. Dihydroquercetin waxay leedahay laba atom oo dheeraad ah oo hydrogen ah halkii molecule, taas oo ka dhigaysa antioxidant aad u xoog badan, sida laga soo xigtay daraasado hore oo caafimaad.
3. Taxifolin (dihydroquercetin) maaha mutagenic oo ka sun yar quercetin. Waxay u shaqeysaa sidii wakiilka kiimikaad ee suurtagalka ah iyadoo nidaamisa hiddo-wadaha iyada oo loo marayo hab ku tiirsan ARE. Taxifolin waxay muujisay inay joojiso koritaanka unugyada kansarka ugxan-sidaha hab ku-tiirsanaan ah.
Maxay yihiin dhibaatooyinka soo raaca Taxifolin (dihydroquercetin)?
Inkasta oo faa'iidooyinka caafimaad ee taxifolin ay leedahay, waxyeellooyin ayaa sidoo kale laga yaabaa inay ku dhacaan dadka qaarkood, gaar ahaan kuwa u qaata flavonoid kaabis cunto ah. Dhibaatooyinka soo raaca taxifolin waxaa ka mid noqon kara:
-Calool xanuun
-Labo iyo shuban
Finan ama dermatitis xiriir
-Khatarta xinjirowga dhiigga iyo dhiig-baxa oo kordha (dadka qaar)
La tasho dhakhtarkaaga ka hor intaadan qaadan taxifolin supplements.
Sidee Vitamin C iyo Taxifolin Dihydroquercetin u wada shaqeeyaan?
Taxifolin waxay kordhisaa saamaynta faa'iidada leh ee fitamiin C iyada oo kordhinaysa muddada hawlaheeda bayoolojiga, kicinta dib u soo kabashada iyo hoos u dhigista ka saarida jirka. Ruushka, isku-dhafan taxifolin iyo fitamiin C waa daaweyn caan ah oo loogu talagalay cudurro badan halkaas oo cadaadiska oksaydhku yahay habka hoose.
iibso Taxifolin (dihydroquercetin) budada online
Taxifolin (dihydroquercetin) waa bioflavonoid leh saameyn xoog leh oo ka hortagga bararka iyo antioxidant. Flavonoid-ka waxaa laga helaa cuntooyinka iyo cabitaannada sida khamriga, shaaha, kookaha iyo khalka, oo ay la socdaan miro iyo khudaar badan. Taxifolin waxay u adeegi kartaa dhowr ujeedo caafimaad sida ka hortagga bararka iyo wakiilka kansarka.
Taxifolin (dihydroquercetin) ayaa laga heli karaa oo ka iibsan kartaa suuqa qaab budo cayriin ah. Wisepowder waxay awood u leedahay inay soo saarto oo ay bixiso tiro badan oo budada Taxifolin (Dihydroquercetin). Wisepowder waxay leedahay shaybaar madaxbannaan iyo
kooxda cilmi sayniska xirfadeed, nidaamka maaraynta tayada adag, qalabaysan qalab horumarsan laga keeno Germany, Japan iyo US falanqaynta iyo synthesize ee content ee maaddooyinka firfircoon, dammaanad alaabta iyo adeegga tayada ugu fiican. Waa lagugu soo dhawaynayaa in aad kala hadasho tafaasiil dheeri ah oo aad dhisto wada shaqayn wakhti dheer ah.
Taxifolin (dihydroquercetin) budada 480-18-2 Tixraaca
- 1. Angelis A, iyo al. Go'doominta-Bio-Hagayay ee Metabolites-ka-milmi kara ee Metabolites ee Spruce Caadiga ah (Picea abies) Alaabooyinka Jilif iyo Baadhista Guryahooda Dermo-Cosmetic. Unugyada. 2016 Nov 21;21(11):1586.
- Xidhiidhada dhaqdhaqaaqa qaab-dhismeedka-antioxidant ee flavonoids iyo asiidhyada phenolic: CA Rice-Evans, et al.; Radic Free. Biyo. Med. 20, 933 (1996), (Dib u eegis), Abstract;
- Lei Ren, iyo al. Saamaynta Waxtarka iyo Habka dheef-shiid kiimikaadka ee Taxifolin ee Fibrosis Kelyaha iyadoo loo marayo Habka Kala duwanaanta iyo Waxqabadka aadka u sarreeya Farmashiyaha hore. 2021 Jan 14;11:608511.
- Cadaadiska cytotoxicity hydroperoxide ee polyphenols: T. Nakayama; Kansarka Res. 54, 1991s (1994), Abstract; Xakamaynta cytotoxicity firfircoon ee ogsijiinta ay keento flavonoids: T. Nakayama, et al.; Biochem Farmashiyaha. 45, 265 (1993), Abstract;
- Luo, Haitao; Jiang, Bing-Hua; Boqor, Saarah; Chen, Yi Charlie (2008). "Xakamaynta Kobaca Unugyada iyo Muujinta VEGF ee Unugyada Kansarka Ovarian-ka ee Flavonoids". Nafaqada iyo Kansarka. 60 (6): 800–9. doi:10.1080/01635580802100851. PMID 19005980. S2CID 43576449
