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Budada Emoxypine (2364-75-2)

Budada Emoxipine waxaa loo isticmaalaa daaweynta dhiig-karka hoosaadka iyo dhiig-baxa maskaxda, angioretinopathy, dhexda iyo xididdada ku dhaca qaybta hoose ee xididada xuubka maskaxda, xididdada dhiigga ee xididdada dhiigga ee salkeeda iyo laamaheeda, iwm.

Soo-saar: Soosaaris Dufcaddii
Xidhmada: 1KG / bac, 25KG / durbaan
Caqligu wuxuu awood u leeyahay inuu soo saaro oo uu bixiyo tiro badan. Dhammaan wax soo saarka ee hoos yimaada xaaladda cGMP iyo nidaamka xakamaynta tayada adag, dhammaan dukumeentiyada imtixaanka iyo muunada la heli karo.

Budada Emoxypine (2364-75-2) fiidiyow

 

Macluumaadka Saldhigga budada Emoxypine

magaca Budada Emoxypine
CAS 2364-75-2
xagiisayna 98%
Magaca kiimikada Mexidol; Mexifin
Isku mid ahaanshaha Emoxipin, Emoxypin, Epigid, 6-Methyl-2-ethyl-3-hydroxypyridine
Formula kelli C8H11NO
Miisaanka kelli 137.179 g g / mol
Dhibicda Biyaha 170 ilaa 172 ° C
Muhiimadda InChI JPGDYIGSCHWQCC-UHFFFAOYSA-N
Form Solid
Imaanshaha Caddaan illaa Caddaan-cadcad ah
Nolosha badh 2-2.6 saacadood
milmi Biyaha si aad ah ugu milma; DMSO (Wax yar); Methanol (Wax yar)
kaydinta Xaaladda 0 - 4 C muddo gaaban (maalmo illaa toddobaadyo), ama -20 C muddo dheer (bilo).
Codsiga RAD140 waa baaritaan iyo daaweeyn aan xakameynin xayeysiiyaha xajmiga (SARM) ee daaweynta xaaladaha sida murqaha luminta iyo kansarka naasaha.
Dukumentiga Tijaabinta Available

 

Budada Emoxypine Sharraxaadda Guud

Budada Emoxypine (2-ethyl-6-methyl-3-hydroxypyridine) budada, oo sidoo kale loo yaqaan Mexidol ama Mexifin markii loo isticmaalo cusbada succinate, waa antioxidant-ka lagu sameeyay Russiaby Pharmasoft Farmashiyeyaasha. Qaab dhismeedkeeda kiimikada wuxuu u egyahay midka Pyridoxine (nooc ah fitamiin B6).

 

Budada Emoxypine (2364-75-2) Taariikhda

Budada Emoxypine waxaa markii ugu horreysay isku-dubariday LD Smirnov iyo KM Dumayev, ka dibna waxay ku barteen oo ay ku barteen machadka Farmacolojiyada, Akademiyada Ruushka ee Sayniska Caafimaadka iyo Xarunta Sayniska Qaranka ee Aaladda Wax-ka-bedelka Sunta Noolaha.

 

Emoxypine (2364-75-2) Farsamooyinka Ficil

Farsamada Emoxypine ee ficilka ayaa la rumeysan yahay inay tahay saameynteeda antioxidant iyo xuubka-xuubka leh qaybaha muhiimka ah ee soo socda:

  • Emoxypine waxay xaddideysaa oksidaynta xagjirka ah ee lipids bio biorane, waxay ka falcelisaa xagjirka peroxide ee lipids-ka asaasiga ah iyo hydroxyl xagjirka ah ee peptides
  • Waxay kordhisaa waxqabadka enzymes-ka antioxidant, qaasatan kuwa superoxide dismutase, mas'uul ka ah sameynta iyo isticmaalka liinta peroxides iyo qaababka oksijiinta firfircoon
  • Waxay joojineysaa xag-jiryo bilaash ah inta lagu gudajiro isku-duwaha 'prostaglandin catczed cyclooxygenase' iyo 'lipoxygenase', waxay kordhisaa isku-xidhka suuxdinta prostacyclin / thromboxane A2and waxay xannibtaa sameynta leukotriene
  • Waxay kordhineysaa waxyaabaha kujira jajabka polar ee lipids (phosphatidyl serine iyo phosphatidyl inositol) waxayna yareyneysaa saamiga kolestaroolka / fosfoolojiyadda taas oo cadeyneysa sifooyinka xakameynta lipid; u wareejisa wareejinta qaab-dhismeedka aagagga heerkulka hooseeya, taas oo ka xanaajineysa yareynta aragtida xuubka iyo kordhinta dheecaanka, waxay kordhisaa saamiga borotiinka.
  • Wuxuu dejiyaa waxqabadka enzymes-membrane-kuxiran: phosphodiesterase, cyclicnucleotides, adenylate cyclase, aldoreductase, acetylcholinesterase.
  • Wuxuu qaabeeyaa qaabdhismeedka receptor ee xuubabka maskaxda, tusaale ahaan benzodiazepine, GABA, acetylcholine receptors ayagoo kordhinaya awoodooda isku xirnaanta.
  • Waxay xasilisaa biomembranes, yacni qaab dhismeedka xuubka unugyada dhiigga - erythrocytes iyo thrombocytes inta lagu jiro haemolysis ama dhaawaca farsamo oo ay weheliso sameynta xagjirnimo bilaash ah.
  • Wuxuu badalaa heerka monoamine-ka wuxuuna kordhiyaa maadada dopamine-ka maskaxda.

Emoxypine (2364-75-2) Codsi

Gudaha Ruushka, emoxypine waxay leedahay codsiyo aad u kala duwan xagga dhaqanka caafimaadka. Waxay si cad u sheegtaa walaaca, ka-hortagga cadaadiska, ka-hortagga khamriga, ka-hortagga, nootropic, neuroprotective iyo tallaabo anti-bararka. Emoxypine waxay u badan tahay inay hagaajiso wareegga dhiigga ee maskaxda, waxay horjoogsataa isku -darka thrombocyte, waxay hoos u dhigtaa heerarka kolestaroolka, waxay leedahay ficil wadne -wadne iyo antiatherosclerotic.

 

Emoxypine (2364-75-2) Cilmi Baaris Dheeraad ah

Hal daraasad ayaa go'aamisay waxtarka emoxypine ee bukaannada 205 ee leh astaamaha caafimaad ee lumbosacral radiculopathy (LSR). Bukaanka ayaa loo qaybiyay laba qaybood, iyo in ka sii badan ayaa loo qaybiyay koox hoosaadyo iyada oo kuxiran jiritaanka rabshadaha mooto. Dhammaan bukaannadu waxay heleen koorso daaweynta caadiga ah iyo daaweynta dabiiciga ah; kooxda ugu weyn ee intaa ka sokow waxay heleen ecxypine. Ka dib, xakameynta bukaan-eegtada ee natiijooyinka muddada-dheer ee daaweynta ee koox hoosaadka bukaannada ayaa la qabtay. Natiijooyinka waxay muujiyeen in isticmaalka emoxypine ee daaweynta isku dhafka ah ee bukaanka qaba LSR ay horseedeen hoos u dhac weyn oo joogto ah oo ku saabsan xanuunka xanuunka iyo dib u soo kabashada dhakhsaha ah ee xididdada laf-dhabarka iyo dareemayaasha durugsan marka la barbar dhigo daaweynta caadiga ah.

 

Emoxypine (2364-75-2) Tixraac

[1] Dumayev KM, Voronina TA, antirid-ka loo yaqaan 'smirnov LD antioxidants' ee prophylaxis iyo daaweynta CNS pathologies. Moscow, 1995

[2] Kucheryanu, VG (Janawari 2001). "Mexidol wuxuu awood uleeyahay saameynta antiparkinsonian ee L-DOPA ee qaabdhismeedka cudurka Parkinsonism ee MPTP". Eksperimental'naia i klinicheskaia farmakologiia. 64 (1): 22-25.

[3] Likhacheva, EB; Sholomov, II (2006). "Qiimeynta bukaan socodka iyo difaaca jirka ee mexidol ee daaweynta lumbosacral radiculopathy". ZhurnalNevrologii i Psikhiatrii Imeni SS Korsakova. 106 (10): 52-7.
 

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