Salidroside (Rhodioloside) budada 10338-51-9

Salidroside (Rhodioloside) budada 10338-51-9 Macluumaadka Saldhigga Kiimikada

Salidroside (Rhodioloside) budada 10338-51-9 General Description

Salidroside (rhodioloside) budada waa glucoside of tyrosol oo laga helo geedka Rhodiola rosea. Waxaa la dersay, oo ay weheliso rosavin, oo ah mid ka mid ah xeryahooda suurtagalka ah ee mas'uul ka ah ficillada antidepressant-ka ah iyo falalka anxiolytic ee geedkan. Salidroside waxaa laga yaabaa inay ka firfircoonaato rosavin.

Caddaymaha soo baxaya waxay muujinayaan in salidroside, daawo bey'ad la qabsatay oo rajo leh oo leh sun yar waxyeellooyin, waxay leedahay noocyo kala duwan oo daawooyinka farmashiyaha ah, oo ay ku jiraan hawlaha nidaamka wadnaha iyo habka dhexe ee neerfayaasha, anti-hypoxia, anti-daal and anti-gabowga, hawlaha anti-kansarka, hawlaha anti-bararka, firfircoonida antioxidant, anti-virus iyo hawlaha kicinta difaaca. dhaqdhaqaaqa antidiabetic, hawlaha anti-osteoporotic, iyo wixii la mid ah. Inkasta oo cilmi-baaristii hore ay soo koobtay saameynta dawooyinka ee salidroside, oo diiradda saaraya habka dhexe ee neerfayaasha, sonkorowga, iyo kansarka, guud ahaan dhinacyada dawooyinka ee aan la falanqeyn.

Salidroside (Rhodioloside) budada 10338-51-9 Mfarsamada Of Action

Sidee bay Salidroside (Rhodioloside) budada uga shaqeysaa gudaha jirka iyo waa maxay faa'iidooyinka Salidroside?

Salidroside (Rhodioloside) budada, phenylpropanoid glycoside oo ka go'an Rhodiola rosea, ayaa lagu soo warramey inay leedahay noocyo badan oo daawooyinka farmashiyaha ah. Salidroside waa prolyl endopeptidase inhibitor. Salidroside waxay yaraynaysaa calaamadaha cachexia ee moodooyinka jiirka ee kansarka cachexia iyada oo la kicinayo calaamadaha mTOR. Salidroside waxay ilaalisaa dopaminergic neurons iyadoo kor u qaadaysa PINK1/Mitophagy dhexdhexaadin ah ee Parkin.

Budada Salidroside waxay joojisaa koritaanka khadadka unugyada kansarka ee kala duwan ee bini'aadamka ee feejignaanta-iyo hababka ku-tiirsanaanta waqtiga, iyo dareenka salidroside waa ka duwan yahay khadadka unugyada kansarka. Salidroside waxay sababi kartaa G1-wajiga ama G2-wajiga xiritaanka khadadka unugyada kansarka ee kala duwan, Dhanka kale, salidroside waxay keentaa hoos u dhaca CDK4, cyclin D1, cyclin B1 iyo Cdc2, waxayna kor u qaadaysaa heerarka p27 (Kip1) iyo p21 (Cip1). Salidroside waxay sidoo kale yaraynaysaa luminta jiritaanka unugyada iyo dhimashada unugyada apoptotic ee ay keentay H (2) O (2) kicinta ee NGF-ga duwan ee unugyada PC12 iyada oo la kicinayo jidka ERK1 / 2 iyo joojinta kicinta caspase-3. Salidroside waxa ay hawlgelisaa dariiqa PI3K/Akt taas oo keenta saamayn ka hortag ah oo ka dhan ah MPP(+) apoptosis-ku keeno unugyada PC12, kaas oo loo isticmaali karo daawaynta cudurka Parkinson (PD).

Salidroside (Rhodioloside) budada 10338-51-9 Codsiga

Salidroside waa mid ka mid ah glycoside-ka weyn ee laga soo saaro Rhodiola rosea, maxay yihiin isticmaalka iyo faa'iidooyinka Salidroside (Rhodioloside)? Waa maxay Salidroside (Rhodioloside) budada loo isticmaalo?

Salidroside, 8-O-β-D-glucoside of tyrosol, waa qaybta ugu muhiimsan ee noolaha ee noocyada Rhodiola waxaana laga helaa inta badan xididdada geedka. Waxay ku dhex jirtaa dheef-shiid kiimikaadka tyrosine-ka, iyadoo glucosylation of tyrosol ay tahay tallaabada ugu dambeysa. Waxaa lagu soo warramey inay tahay neuroprotective iyo mid ka mid ah xeryahooda ka mas'uulka ah ka hortagga niyad-jabka iyo falalka anxiolytic ee Rhodiola rosea.

Salidroside (Rhodioloside) waxay muujin kartaa noocyo kala duwan oo dawooyin ah sida anti-gabowga, anti-oxidant, anti-kansarka iyo ka hortagga bararka.

Salidroside (Rhodioloside) faa'iidooyinka waa:

1. Anti-Alzheimer cudurka saamaynta
2. Saamaynta cudurka Parkinson
3. Saamaynta ka hortagga istaroogga
4. Aqoonsiga xoojin
5. Ka-hortagga niyad-jabka iyo saamaynta anxiolytic
6. Wanaajinta dhaawaca maskaxda ee dhaawaca ah
7. Saamaynta cudurka Anti-Huntington
8. Saamaynta ka hortagga balwadda
9. Saamaynta ka hortagga suuxdinta

Salidroside (Rhodioloside) budada waxay u isticmaali kartaa:

1. cuntada
2. sharaabka
3. supplements cuntada
4. daawo

Salidroside (Rhodioloside) budada 10338-51-9 ammaanka

Ammaan ma tahay in la isticmaalo Salidroside (Rhodioloside) iyo maxay yihiin waxyeellooyin Salidroside (Rhodioloside)?

Salidroside waxaa badanaa loo arkaa inay tahay walax badbaado leh oo waxtar leh. Waxaa la soo gabagabeeyay in salidroside aysan keenin sunta hooyada ama uurjiifka, mana jiraan wax saameyn ah oo teratogenic ah oo hoos yimaada xaaladaha tijaabada ee qiyaasta 0.5, 0.25, iyo 0.125 g / kg ee jiirka SD.88 Qiimaynta Genotoxicity ayaa lagama maarmaan u ah khatarta. qiimaynta daroogada. Natiijooyinka baaritaanka Ames, baaritaanka isbeddelka isbeddelka, baaritaanka cilladaha koromosoomyada, iyo jiirka micronucleus assay ayaa muujiyay in salidroside uusan ahayn genotoxic qiyaasta bukaan-socodka (150 mg / 60 kg / day) ee bini'aadamka.89,90 Tijaabo kale oo la kala soocay oo la xakameynayo Kiisaska 60 ee kansarka naasaha ayaa muujiyay in aysan jirin dhacdooyin liddi ku ah kiliinikada marka qiyaasta waxtarka leh ee salidroside (600 mg / kg / day) la maamulay inta lagu jiro habka daaweynta oo dhan. Sidaa darteed, la'aanta saameynaha xun ee koorsada hore ee kiliinikada iyo kiliinikada Tijaabooyinku waxay muujinayaan in salidroside ay u ballan qaadayso dawo caafimaad oo caadi ah.

Waa maxay faraqa u dhexeeya rosavin iyo salidroside?

Rosavin wuxuu ahaa mid aad uga firfircoon fiirsashada sare marka loo eego salidroside; halka, salidroside ay aad waxtar ugu lahayd xaddi hoose. Nuxurka ugu sarreeya ee labada calaamadood ee firfircoon ayaa laga helay soosaarayaasha kuwaas oo ahaa kuwa firfircoon ee ugu hooseeya

iibso Salidroside (Rhodioloside) budada online

Salidroside , Glucoside of tyrosol ayaa si fiican loo aasaasay oo ah qaybta ugu muhiimsan ee bioactive ee Rhodiola (sidoo kale loo yaqaan "Tibetan Ginseng"), taas oo ah geedo dawo ah oo aad loo qiimeeyo oo ku koraa meel sare iyo gobollada qabow, sida jiirarka Himalayas. . Faa'iidooyinkeedu waxay dib ugu noqdaan taariikh dheer oo isticmaalka dadweynaha.

Sababtoo ah korriintiisa gaabis ah iyo ururinta xad-dhaafka ah, khayraadka Rhodiola duurjoogta ah ayaa ku yaal cidhifka daalka. Intaa waxaa dheer, waxa ku jira salidroside ee Rhodiola waa mid aad u hooseeya. Sidaa darteed, si loo daboolo baahida sii kordheysa ee Salidroside, dadaallo badan ayaa la sameeyay si kor loogu qaado wax soo saarka salidroside ilaa sanado badan.

Wisepowder sida soo saaraha diiradda saaraya cilmi-baarista, wax-soo-saarka iyo hal-abuurka alaabta ceeriin ee loogu talagalay nootropics, Kaabayaasha nafaqeynta iyo maaddooyinka dawooyinka muddo tobanaan sano ah. Sida soo saaraha ee Salidroside (Rhodioloside) budada, Wisepowder ku fiican isticmaalka tignoolajiyada halsano si loo soo saaro budada Salidroside, dammaanad bixinta budada Salidroside, iyo nadiifinta budada Salidroside aan ka yarayn 98%, daboolo baahiyaha qaybiyeyaasha, alaab-qeybiyeyaasha cuntada dheeraadka ah.

Salidroside (Rhodioloside) budada 10338-51-9 Tixraaca

1. Mao Y, Li Y, Yao N (Noofambar 2007). "Go'aaminta isla mar ahaantaana ee salidroside iyo tyrosol ee laga soosaaray Rhodiola L. by mikrowave caawin soo saarista iyo chromatography dareere waxqabadka sare". Joornaalka Falanqaynta Dawooyinka iyo Biyo-daweynta. 45 (3): 510- doi:10.1016/j.jpba.2007.05.031. PMID 17628386
2. Panossian A, Nikoyan N, Ohanyan N, Hovhannisyan A, Abrahamyan H, Gabrielyan E, Wikman G (Janaayo 2008). "Daraasadda isbarbardhigga ah ee diyaarinta Rhodiola ee rajo-xumada dabeecadda ee jiirka" Phytomedicine. 15 (1–2): 84–91. doi:10.1016/j.phymed.2007.10.003. PMID 18054474
3. H. Zhong et al.Salidroside waxay hoos u dhigtaa apoptosis ee wadnaha wadnaha ischemic: habka loo maro dariiqa ku-tiirsanaanta mitochondria 1.Pharmacol. Saynis (2010)
4. Z. Qi et al.Salidroside waxay hoos u dhigtaa jawaabta bararka iyada oo la xakameynayo dhaqdhaqaaqa JAK2-STAT3 iyo ka hortagga u wareejinta STAT3 ee nucleusInt. Immunopharm. (2016)
5. Koshkin, V., Wang, X., Scherer, PE, Chan, CB, iyo Wheeler, MB (2003). Mitochondrial functional in clonal pancreatic beta-unugyada ay la kulmaan asiidh dufan ah oo bilaash ah. J. Biol. Chem. 278, 19709–19715.doi: 10.1074/jbc.M209709200